Critically ill COVID-19 sub phenotypes and differential treatment effects

Professor Manu Shankar Hari provides an overview of recently published work on the preliminary data on validation of critically ill COVID-19 patients.

• Review phenotypes and endotypes
• Review method and results of recent paper; who was studied, what was measured and subphenotypes
• Gain knowledge of treatment effect differences
• Review the strengths and limitations of the cohort

Professor Manu Shankar Hari is the chair of translational critical care medicine at the University of Edinburgh.

His research goal is to enable precision immunomodulation in critically ill adults, with a core hypothesis that modifiable networks generate clinical phenotypes, and such networks could be determined by integration of clinical and immunobiology data.