This Grand Round presented by Dr Amanda Sathyapala focuses on CPAP adherence in patient with obstructive sleep apnea.
Dr Amanda Sathyapala Background
Dr Amanda Sathyapala is a consultant respiratory physician, and clinical lead of the home ventilation service at Harefield hospital.
She is also a senior lecturer in the airways disease section of the National Heart and Lung Institute of Imperial College London.
Her clinical expertise includes respiratory failure, particularly chronic ventilatory failure requiring non-invasive ventilation, as a result of conditions such as COPD, bronchiectasis, chest wall disease, lung fibrosis, or following surgery. She also specialises in diagnosis and management of respiratory muscle weakness as well as sleep-disordered breathing, such as obstructive sleep apnoea and obesity hypoventilation syndrome.
She is one of only a few respiratory physicians delivering cognitive behavioural therapy for insomnia.
This talk covers the topic of primary care and the cardiac patient. This is a broad subject which Professor Rosen has narrowed down to cover the below 5 topic.
Professor Stuart Rosen Background
Professor Stuart Rosen is a consultant cardiologist who along with Dr Lyon and Dr Sharma set up the UK’s first cardio-oncology unit at Royal Brompton Hospital.
The unit provides bespoke care for those patients who have developed cardiac problems or are at risk of cardiotoxicity as a result of their cancer treatment.
He is also passionate about education and teaching on cardiology where he speaks on topics such as cardiac pain, heart failure and neurocardiology. He is a consultant cardiologist specialising in treating difficult hypertension, syncope, heart failure and all aspects of general adult cardiology.
Additionally, his expertise in technical skills include stress echo, ultrafiltration for decompensated heart failure, tilt testing and autonomic assessment and transoesophageal echocardiography
The British Heart Foundation and Medical Research Council have both funded Professor Rosens’ cardiovascular research in: effect of alcohol excess on heart function, mechanisms of heart injury in cancer patients, origins of complex cardiac pain syndromes, and role of cardiac autonomic dysfunction in pathophysiology of cardiac disease.
Moreover, professor Rosen has written numerous peer-reviewed articles, papers, abstracts, editorials and eight book chapters as well as writing a book, ‘Cardiology: Self assessment Colour Review’, published by CRC Press.
Professor Rosen has twice been awarded a prize for excellence in clinical teaching by the faculty of medicine and he supervises postgraduate, MD and PhD students. He also has extensive teaching commitments in ethics and law, medicine and cardiology for medical undergraduates.
This talk by Professor Polkey titles “Spleep: Worth Getting out of Bed for?” covers the topic of sleeps in patients with sleep apnea and how treatment can improve this disorder.
Professor Michael Polkey Background
Professor Michael Polkey is an academic and continues as a professor of respiratory medicine at Imperial College London.
Both Qatar and Kuwait invited him as a professor due to his expertise and knowledge in respiratory medicine and also acts in a clinical capacity in providing second opinions on patient diagnoses.
Moreover, professor Polkey specialises in many respiratory conditions, including: chronic obstructive pulmonary disease (COPD), respiratory aspects of neurological disease, advanced lung disease which results in respiratory failure, sleep disordered breathing, emphysema, diaphragm disease.
In particular, he is an expert in the management of chronic respiratory failure, treating COPD, weaning patients from invasive mechanical ventilation and he is an expert in neurological diseases as motor neurone disease (MND) known as amyotrophic lateral sclerosis (ALS) and Lou Gehrig’s disease.
The National Institute for Health Research (NIHR) funds the respiratory biomedical research unit at Royal Brompton Hospital and Professor Polkey is the deputy director. Prof Polkey acquired and directed many multi-faceted research projects, with many focused around COPD.
He has nearly 200 published scientific articles and sits as an associate editor for the European Respiratory Journal and Clinical Science. He is active on the board of Skeletal Muscle and the COPD journals and is well established in reviewing for all other major respiratory journals.
Professor Polkey supervises and examines PhD students at Imperial College London, and trains overseas students at Royal Brompton Hospital. He is also in demand on a global level as an international speaker.
This talk by Professor Nicholas Hart focuses on the “Game Changing trials in Home Mechanical Ventilation”.
Professor Nicholas Hart Background
He is professor of respiratory and critical care medicine, Faculty of Life Sciences and Medicine, School of Basic and Medical BioSciences, King’s College London. He is also director of research and development delivery, Guy’s and St Thomas’ NHS Foundation Trust. And joint editor-in-chief, Thorax.
Lane Fox Respiratory service, an internationally recognised weaning, rehabilitation and home mechanical ventilation service, appointed Nicholas as the director in April 2012. Since taking over, he has increased the activity by the introduction of seven-day working, opened the Lane Fox-REMEO Centre, re-structured the outpatient clinics, outpatient service and home ventilation service and increased the acuity of the inpatient service with installation of a comprehensive electronic patient record and central monitoring system. This has required an enhancement of the specialist workforce including consultants, junior doctors, nurses, allied health care professionals, technicians and administrative staff to support the service across paediatrics and adults.
Nicholas has developed a technology that has an intellectual property patent in the Europe (US pending) and this has resulted with close collaborative industry links with Philips. He has a master research agreement with Philips to develop and commercialise the Myotrace technology, which involved supervising a signal processing engineer working in the Lane Fox Clinical Respiratory Physiology Research Centre. Nicholas was appointed to the Philips Global Executive Pulmonary Advisory Board in 2014 with a primary role to identify and develop new technologies for respiratory health.
Nicholas’ research has received a total grant income of over £7 million with over £3.5 million in grants as lead applicant or primary supervisor since 2007.
Since 2009, he has successfully supervised seven students coming from the following universities: King’s College London PhD students, University College London, and Oxford University.
This talk by Dr Alexander Lyon on “heart problems in cancer patients and the new ESC cardio-oncology guidelines” sheds light on how modern cancer therapies cure cancer but might cause heart problems.
Dr Alexander Lyon Background
Dr Alexander Lyon, consultant cardiologist is the heart failure team lead and the cardiovascular biomedical research unit lead at Royal Brompton & Harefield Hospitals.
He studied at the University of Oxford, then trained as a junior doctor in cardiology in Oxford, London and also in Sydney, Australia. In 2005, he was awarded an MRC Clinical Research Training Fellowship and studied the influence of cardiac gene therapy on ventricular arrhythmia generation. In 2008 he completed his PhD and finished his cardiology training at St Mary’s Hospital and Royal Brompton Hospital.
Moreover, he has received several academic awards from the British Society for Cardiovascular Research, British Cardiovascular Society, Medical Research Society, International Society of Heart Research and the Royal Society of Medicine.
Dr Alexander Lyon is an expert in hypertension, heart valve disease, coronary artery disease, cardiomyopathy and specialises in heart failure, cardiac gene therapy, Takotsubo syndrome, cardiovascular diseases caused by cancer treatments, known as cardio-oncology, chemotherapy-induced heart failure and novel molecular and biological therapies for heart failure. He runs a specialist clinic focusing on risk prediction and management of refractory symptoms for patients with Takotsubo syndrome.
Dr Lyon also specialises in the investigation of cardiac symptoms like breathlessness, dizzy spells, chest pain, palpitations, and general cardiac health checks to guide risk factor management.
Dr Alexander Lyon is a senior lecturer at Imperial College London, where he supervises PhD students. He has presented at national and international meetings on regenerative medicine therapy in heart failure, chemotherapy-induced cardiac dysfunction and heart failure, cardiac calcium pathophysiology and Takotsubo cardiomyopathy
Prof. Thomas Muenzel covers the impacts and effects that Environmental Hazards have on Cardiovascular Disease.
Professor Thomas Muenzel Background
Professor Muenzel is currently the Chairmain of the Department of Cardiology at the University Medical Centre in Mainz, Germany.
Prof. Muenzel had published vastly in vascular biology and cardiology, alike; He made major contributions in the molecular mechanism and clinical effects of nitroglycerin and most recently, has focused his interest on environmental injuries on the cardiovascular system and its implications for cardiovascular health and disease; he has really pioneered this field that is currently centre stage worldwide. Based on his work he coined the term “exposome” as a new focus in cardiovascular prevention including environmental injuries.
He also held a faculty position at the University Hospital Eppendorf, Hamburg and has help his position since 2004.
SARCOIDOSIS IN PRIMARY CARE
This short talk on “Sarcoidosis in Primary Care” aims to assist general practitioners to consider sarcoidosis as a possible explanation for patients presenting with typical as well as non-specific symptoms and signs suggestive of this disease.
Early consideration of sarcoidosis as a possibility and referral to specialist sarcoidosis centres by GPs could prevent progression of symptoms and speed up the identification of extra pulmonary complications that can be life-threatening
DR. VASILIS KOURANOS BACKGROUND
Dr Vasilis Kouranos completed his training in respiratory medicine in 2013 at the General Hospital of Thoracic Diseases, in Athens, Greece.
In addittion, he completed his PhD at the University of Athens focused on screening CMR patients with biopsy-proven sarcoidosis. He was awarded a research scholarship for the study and his PhD was awarded in 2017 after his work was published in a high-impact journal.
Dr Kouranos joined the Royal Brompton hospital as a clinical research fellow to Professor Athol Wells. In 2016 he started the role of senior clinical fellow while he was acting consultant in the interstitial lung disease department.
Moreover, he has great experience in management of patients with sarcoidosis, interstitial lung disease and pulmonary fibrosis.
Read more: here
IRON MAN TRIAL OBJECTIVES
The Ironman trial examines the connection between patients with heart failure, reduced left ventricular ejection fraction, iron deficiency, intravenous ferric carboxymaltose administration and whether it improves quality of life and exercise capacity in the short term and reduces hospital admissions for heart failure up to one year. This study aimed to evaluate the longer-term effects of intravenous ferric derisomaltose on cardiovascular events in patients with heart failure.
PROFESSOR PAUL KALRA BACKGROUND
This Grand Round is presented by Professor Paul Kalra. Professor Kalra started as a Consultant Cardiologist at Portsmouth Hospitals NHS Trust in April 2004. In 2019 he was appointed as Honorary Professor of Cardiology.
He is Chief Investigator for the BHF funded Ironman trial study evaluating the role of intravenous iron in patients with heart failure (IRONMAN – 75 UK centres), which has the potential to shape international guidelines and clinical practice.
Whilst he has a broad interest in all aspects of general adult cardiology, his sub-specialty interest is the assessment and management of patients with heart failure. He has championed local heart failure service development spanning primary, secondary and tertiary care. In addition, he co-developed the local complex device service, initiating local implantable cardioverter defibrillator (ICD) and cardiac resynchronisation therapy device (CRT) implantation and follow up. Paul has extensive expertise in assessment of patients for and the implantation of pacemakers and other complex devices (CRT and ICD).
Paul has been on the British Society for Heart Failure Board since 2009 and was elected Chair 2017-2019 (now past chair). This is the national body providing expert advice, support and education to NHS organizations, professionals and patients (working closely with patient groups). During his role as Chair he was instrumental in getting heart failure recognised as a priority and incorporated into the NHS Long Term Plan published in 2019. He is currently helping to drive implementation of change, contributing to NHS England’s NHS Long Term Plan Heart Failure and Heart Valve Disease Expert Advisory Group. He has helped set up and is vice-chair of the committee for the British Heart Foundation (BHF) ‘hope for hearts’ innovation fund (up to £1 million to help support innovation to help deliver better heart failure care).
In 2019 the UK’s largest heart failure patient charity, Pumping Marvellous Foundation, presented Paul with the Platinum patient educator award – recognising extraordinary work towards building awareness of heart failure and advocacy of better systems to improve care for patients.
He is committed to medical education and has helped organise regular national meetings (see www.bsh.org.uk and www.cardiorenalforum.com) for hospital doctors, GPs and specialist nurses. He actively contributes to education of cardiology trainees through roles with national (British Cardiovascular Society) and international (European Society for Cardiology) societies. This has included question writing and exam setting for the European Exam in General Cardiology for 10 years and in 2020 was appointed Chair of the UK standard setting group for this exam.
He has over 100 peer review publications and has edited a textbook ‘Specialist Training in Cardiology’ which was Highly Commended in the BMA Medical Book Competition.
Professor Pallav Shah covers bronchoscopy techniques and how these have evolved over time, providing insights into case studies.
This talk discusses lung disease and respiratory health related to pulmonary medicine, regarding the recent respiratory pandemic.
This talk provides insights into recent published work on the preliminary data on validation of critically ill COVID-19 patients.
This talk focuses on multi-disciplinary discussions around opportunistic targeted AF case findings, utilising innovative ECG technology and how digital transformation is set to change healthcare.
This talk provides insights into the crystal accumulation and mucus plugging as a driver of severe asthma of type 2 immunity.