The road-map to precision medicine in pulmonary fibrosis

• • Multiple intersecting genetic and environmental pathway change over time

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>Wound repair and

• base

ment membrane inte

grity are critical ‘destinations’
• Epithelial inquiry is a key event in IPF
• TGFB is a critical biological node
• Mechanotransduction and G protein signalling are critical routes

• Promote an understanding of the road-map in the treatment of pulmonary fibrosis

Professor Gisli Jenkins clinical focus is on interstitial lung disease and idiopathic pulmonary fibrosis in particular. Currently, he is the Familial Pulmonary Fibrosis lead for the Genomics England Clinical Interpretation Partnership in Respiratory Medicine and is Post Hospitalisation (PHOSP)-COVID study Fibrosis Working Group lead, also leading the UK interstitial Lung Disease consortium.